Professor
Email: zheli@nju.edu.cn
Research Field: DNA nanotechnology; DNA origami; Self-assembly of DNA structures and functional nanomaterials; Disease diagnostics; Drug delivery
Course: Molecular Biology
Profile:
Professor Li received her bachelor’s from the School of Life and Sciences, Peking University. In 2012, she received her doctorate in biochemistry from Arizona State University and went to Yale University for post-doctoral research. In 2015, she was selected into the 11th group of the Overseas Young Scholars Project of China and joined the Department of Biomedical Engineering, College of Engineering and Applied Science, Nanjing University.
Her research focuses on the biomedical applications of DNA nanostructures, including disease diagnostics and targeted drug delivery. She has published her research results on top-notch chemistry journals such as Nature Chemistry and Angewandte Chemie International Edition.
Selected Publications:
Spatially Preorganized Hybridization Chain Reaction for the Prompt Diagnosis of Inflammation, Angewandte Chemie International Edition, 2025
DNA Nanostructures Treat Inflammatory Bowel Disease through ROS Scavenging and Gut Microbiota Modulation, Advanced Functional Materials, 2024
Multipathway Regulation for Targeted Atherosclerosis Therapy Using Anti-miR-33-Loaded DNA Origami, ACS Nano,2024
DNA Origami as a Nanomedicine for Targeted Rheumatoid Arthritis Therapy through Reactive Oxygen Species and Nitric Oxide Scavenging, ACS Nano, 2022
Fast and specific enrichment and quantification of cancer-related exosomes by DNA-nanoweight-assisted centrifugation, Analytical Chemistry, 2022
Co-delivery of Chemotherapeutic Drugs and Immune Adjuvants by Nanoscale DNA Tetrahedrons for Synergistic Cancer Therapy, ACS Applied Nano Materials, 2022
An RNA-cleaving threose nucleic acid enzyme capable of single point mutation discrimination, Nature Chemistry, 2022
